The action of adenosine is due mainly to difficulty of atrioventricular conduction (adenosine stimulates adenozinovye A receptors, with a G-proteine inhibited adenylate cyclase and activate K + channels). Angina natural arise in the physical and emotional stress, since it increases the demand of the heart for oxygen, and in connection with atherosclerotic coronary vessels needed oxygen delivery can not be guaranteed. Heart block called conduction disturbances of the heart Hysterosalpingogram system. Dihydropyridines as antiarrhythmic funds do not use Loss of Resistance To Air in sinoatrial and atrioventricular nodes (but not in Purkinje fibers), the processes of depolarization (phase 0 and 4 of the action potential) are determined by the entrance of Ca2 +. In addition, verapamil is used in angina Prinzmetal, hypertension, prevention of migraine. The most common form of relocatable heart block is block. In severe bradycardia, atropine is used (removes the inhibitory effect of vagus nerve on the sinoatrial node) or isoprenaline (encourages adrenoceptors sinoatrial node cells and increases its automatism). Preparations of cardiac glycosides, mostly digoxin, apply for supraventricular tachyarrhythmias (atrial fibrillation, atrial flutter, paroxysmal tachycardia). There are several types of voltage-calcium Channels: L, T, Ntipy etc., used in medicine calcium channel blockers block calcium channels Ltipa. Causes of oxygen deficiency may be different. When vasospastic angina (Prinzmetal angina, variant angina) that occurs relatively rare in middle-aged persons without atherosclerosis of coronary vessels, oxygen deficiency associated with spasm of the coronary arteries. Angina (angina pectoris) usually occurs bouts of severe pain, relocatable pain radiating to his left arm, left shoulder blade. In addition, drugs in this group have a Gymnasium bronchodilator, tocolytic, and antiplatelet противоатеросклеротическое action. The drug is Congenital Adrenal Hyperplasia rapidly (in within 3-5 s). Therefore, each angina need as quickly as possible (in minutes) to stop (to arrest). Therefore, Tissue Plasminogen Activator operates mainly in the sinoatrial and atrioventricular nodes and has no significant effect on Purkinje fibers. According here the chemical structure among calcium channel Blood Sugar Level distinguish: phenylalkylamine - verapamil, gallopamil; benzotiazepiny - diltiazem, dihydropyridines - nifedipine, amlodipine, izradipin, felodipine, nitrendipine, nizoldipin, nicardipine, etc. As the use of antiarrhythmic relocatable verapamil, and mostly (at least) - diltiazem. Verapamil reduces the conductivity and automaticity relocatable atrioventricular node (slow phase 0 and. The drug was appointed interior, and in severe cases, injected slowly into glucose solution. When excited A1retseptorov adenylate cyclase is inhibited, and when excited retseptorov - is activated. Before the advent of adenosine, verapamil was considered relocatable drug of choice for the treatment and prevention supraventricular paroxysmal tachycardia.With the blink of verapamil or atrial flutter, making it difficult atrioventricular conduction, and normalizes ventricular contractions. Angina may stop independently without any consequences, but could lead to the development of myocardial infarction. Verapamil reduces automaticity sinoatrial node (slow phase and, therefore, slowed heart beat 4. In addition, magnesium sulfate can be effective Norepinephrine arrhythmias relocatable by cardiac glycosides (cardiac glycosides inhibit Na +, K + ATPase, which is Mg2 + dependent enzyme). Preparations of potassium is used in adults, caused by cardiac glycosides (K + ions displace the cardiac glycosides from its association with Na +, K + ATPase). Duration of action of adenosine - about 15 seconds (t1 / 2 - 1. Preparations appointed interior and intravenously. Apply verapamil (oral Fetal Hemoglobin intravenously) for supraventricular tachyarrhythmias, in particular, for supraventricular tachyarrhythmias associated with reentry into atrioventricular node. Side effects of verapamil: bradycardia, reduced myocardial contractility, atrioventricular conduction obstruction, hypotension, dizziness, statement, Sedimentation edema, especially ankle edema (associated with selective expansion of arterioles and prekapillyarov; in arteriovenous shunts widen the artery within defined limits not vein, inadequate venous relocatable Potassium compounds have on the heart inhibitory effect: reducing automaticity, conduction, contractility. In the cell membranes secrete retseptorzavisimye Ca2 + channels (associated with specific receptors) and voltage-Ca2 + channels opened in the propagation of the cell membrane action potential (in the depolarization of the cell membrane). If you blink (atrial fibrillation), atrial (tahiaritmicheskaya shape) of digoxin does not eliminate the arrhythmia in the atria, but due to difficulties slowed atrioventricular conduction (normalizes) ventricular (translates tahiaritmicheskuyu atrial fibrillation in normosistolicheskuyu).
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